Biology space

High-Level Project Summary

In the first section you will find a short introduction and a sentence about knowledge, in the second section you will find the five main problems of space with their respective description, in the third section focuses mainly on the risks that humans may have in space travel and also some solutions to these risks, in the fourth section is the effects of some living beings in conditions similar to those of space travel and finally in the fifth section is our proposal of biological superhero.

Detailed Project Description

We read and extracted the most relevant information from the resources provided by NASA in order to translate it into a web page through the WIX platform, then with all this information and with information extracted from websites such as NASA science, BBC NEWS, BBVA mind to create our biological superhero. The benefits we obtained were a knowledge of two great areas such as biology and astronomy, besides being able to create a strong and dynamic group during the development of the challenge. We hope to fully meet all the requirements of the challenge so that we had the opportunity for NASA to publicize the website created for anyone to know how amazing it is all the processes of space travel and life in space. We use WIX and Paint 3D 

Space Agency Data

For the elaboration of the web page, the resources provided by the official page of NASA were taken into account, each resource corresponded to a section of the web page: The NASA human research roadmap, which was used to know all the negative implications of making a space trip; 5 dangers of space flight, was used to give an idea of the risks involved in space flight; NASA's genelab data repository, was used to review the different animals and plants that were carried on space travel and what were the reactions they had under that environment.

https://humanresearchroadmap.nasa.gov/risks/

https://science.nasa.gov/biological-physical/programs/space-biology

https://www.nasa.gov/hrp/5-hazards-of-human-spaceflight

https://genelab-data.ndc.nasa.gov/genelab/projects/

Hackathon Journey

An experience that was too enriching for our social and academic part, since it allowed us to learn about other activities outside our fields of knowledge, and at the same time, discover this type of events that are offered to be able to participate from ideas and projects.

On the other hand, we learned that the problems and unknowns that humanity has in terms of space have endless difficulties but that they can be solved by generating these events so that the student community can contribute brilliant ideas that are reflected in the next missions of these space agencies.

Our team took on this challenge because, in our opinion, it is one of the most important and that the fewest solutions have been proposed, since we know that we are not yet capable of making long trips with a crew, for this reason the idea of ​​generating organisms that can survive against the ostile conditions of space through the help of biology was what amazed us the most.

This group was focused on extracting as much information as possible from the NASA databases so that our website would be a site of good information, as well as being able to inform in a very brief way but it will be accurate the general ideas of this type of problems. such as all the complications and difficulties involved in making an interstellar trip.

In particular, we want to thank the Sergio Arboleda University for making an event of this magnitude possible in its facilities and allowing us to carry out our ideas and project, which we believe may be one of the many solutions to the problem we have faced.

References

Sibonga, J. (2022, julio 29). Concern of Intervertebral Disc Damage upon and immediately after re-exposure to Gravity [inactive]. Nasa.gov. https://humanresearchroadmap.nasa.gov/Risks/risk.aspx?i=78

Whiting, S. (2022, julio 29). Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders. Nasa.gov. https://humanresearchroadmap.nasa.gov/Risks/risk.aspx?i=99

Lehnhardt, K. (2022, julio 29). Risk of adverse health and performance effects of celestial dust exposure. Nasa.gov. https://humanresearchroadmap.nasa.gov/Risks/risk.aspx?i=82

Ott, M. (2022, 15 agosto). Risk of Adverse Health Effects Due to Host-Microorganism Interactions. Nasa.gov. Recuperado 2 de octubre de 2022, de https://humanresearchroadmap.nasa.gov/Risks/risk.aspx?i=80

Crucian, B. (2022, 29 julio). Risk of Adverse Health Event Due to Altered Immune Response. Nasa.gov. Recuperado 2 de octubre de 2022, de https://humanresearchroadmap.nasa.gov/Risks/risk.aspx?i=85

Lehnhardt, K. (2022, 29 julio). Risk of Adverse Health Outcomes and Decrements in Performance Due to Medical Conditions that occur in Mission, as well as Long Term Health Outcomes Due to Mission Exposures. Nasa.gov. Recuperado 2 de octubre de 2022, de https://humanresearchroadmap.nasa.gov/Risks/risk.aspx?i=95

Gore, B. (2022, 29 julio). Risk of Adverse Outcomes Due to Inadequate Human Systems Integration Architecture. Nasa.gov. Recuperado 2 de octubre de 2022, de https://humanresearchroadmap.nasa.gov/Risks/risk.aspx?i=175

Wood, S. (2022, 29 julio). Risk of Altered Sensorimotor/Vestibular Function Impacting Critical Mission Tasks. Nasa.gov. Recuperado 2 de octubre de 2022, de https://humanresearchroadmap.nasa.gov/Risks/risk.aspx?i=88

Lehnhardt, K. (2022b, julio 29). Risk of Bone Fracture due to Spaceflight-induced Changes to Bone. Nasa.gov. Recuperado 2 de octubre de 2022, de https://humanresearchroadmap.nasa.gov/Risks/risk.aspx?i=77

Lee, S. (2022, 29 julio). Risk of Cardiovascular Adaptations Contributing to Adverse Mission Performance and Health Outcomes. Nasa.gov. Recuperado 2 de octubre de 2022, de https://humanresearchroadmap.nasa.gov/Risks/risk.aspx?i=179

Norcross, J. (2022, 29 julio). Risk of Decompression Sickness [inactive]. Nasa.gov. Recuperado 2 de octubre de 2022, de https://humanresearchroadmap.nasa.gov/Risks/risk.aspx?i=168

Aseyev, N. (2017, 1 noviembre). Adaptive Changes in the Vestibular System of Land Snail to a 30-Day Spaceflight and Readaptation on Return to Earth. Frontiers. Recuperado 2 de octubre de 2022, de https://www.frontiersin.org/articles/10.3389/fncel.2017.00348/full

(Aseyev, 2017) (Cita textual)

Chatani, M., Morimoto, H., Takeyama, K., Mantoku, A., Tanigawa, N., Tanigaki, F., Kubota, K., Suzuki, H., Uchida, S., Takano, Y., Shirakawa, M., Gusev, O., Sychev, V., Itoh, T. & Kudo, A. (2016, 22 diciembre). Acute transcriptional up-regulation specific to osteoblasts/osteoclasts in medaka fish immediately after exposure to microgravity. national library of medicine national center for biotechnology information. Recuperado 2 de octubre de 2022, de https://pubmed.ncbi.nlm.nih.gov/28004797/

Zhu, L., Nie, L. N., Xie, S., Meng, E., Zhang, D. & Zhu, L. (2021, 5 enero). Attenuation of Antiviral Immune Response Caused by Perturbation of TRIM25-Mediated RIG-I Activation under Simulated Microgravity. Cell Reports. Recuperado 2 de octubre de 2022, de https://www.cell.com/cell-reports/pdf/S2211-1247(20)31589-8.pdf

(Zhu et al., 2021)

Casey, T., Patel, O. V., & Plaut, K. (2015). Transcriptomes reveal alterations in gravity impact circadian clocks and activate mechanotransduction pathways with adaptation through epigenetic change. Physiological Genomics47(4), 113–128. https://doi.org/10.1152/physiolgenomics.00117.2014

Patel, O. V., Casey, T., Dover, H., & Plaut, K. (2011). Homeorhetic adaptation to lactation: comparative transcriptome analysis of mammary, liver, and adipose tissue during the transition from pregnancy to lactation in rats. Functional & Integrative Genomics11(1), 193–202. https://doi.org/10.1007/s10142-010-0193-0

Casey, T., Patel, O., Dykema, K., Dover, H., Furge, K., & Plaut, K. (2009). Molecular signatures reveal circadian clocks may orchestrate the homeorhetic response to lactation. PloS One4(10), e7395. https://doi.org/10.1371/journal.pone.0007395

Feger, B. J., Thompson, J. W., Dubois, L. G., Kommaddi, R. P., Foster, M. W., Mishra, R., Shenoy, S. K., Shibata, Y., Kidane, Y. H., Moseley, M. A., Carnell, L. S., & Bowles, D. E. (2016). Microgravity induces proteomics changes involved in endoplasmic reticulum stress and mitochondrial protection. Scientific Reports6(1), 34091. https://doi.org/10.1038/srep34091

Genchi, G. G., Degl’Innocenti, A., Salgarella, A. R., Pezzini, I., Marino, A., Menciassi, A., Piccirillo, S., Balsamo, M., & Ciofani, G. (2018). Modulation of gene expression in rat muscle cells following treatment with nanoceria in different gravity regimes. Nanomedicine (London, England)13(22), 2821–2833. https://doi.org/10.2217/nnm-2018-0316

GenelabRepo. (s/f). Nasa.gov. Recuperado el 3 de octubre de 2022, de https://genelab-data.ndc.nasa.gov/genelab/accession/GLDS-422

Higashibata, A., Hashizume, T., Nemoto, K., Higashitani, N., Etheridge, T., Mori, C., Harada, S., Sugimoto, T., Szewczyk, N. J., Baba, S. A., Mogami, Y., Fukui, K., & Higashitani, A. (2016). Microgravity elicits reproducible alterations in cytoskeletal and metabolic gene and protein expression in space-flown Caenorhabditis elegans. NPJ Microgravity2(1), 1–8. https://doi.org/10.1038/npjmgrav.2015.22

Gao, Y., Xu, D., Zhao, L., Zhang, M., & Sun, Y. (2015). Effects of microgravity on DNA damage response in Caenorhabditis elegans during Shenzhou-8 spaceflight. International Journal of Radiation Biology91(7), 531–539. https://doi.org/10.3109/09553002.2015.1043754

News Mundo, B. (2019, 7 agosto). Tardígrados, los organismos con «superpoderes» que (probablemente) están habitando la Luna. BBC News Mundo. Recuperado 2 de octubre de 2022, de https://www.bbc.com/mundo/noticias-49269225

Ciencia a bordo de la misión de carga de SpaceX-22. (s/f). Nasa.gov. Recuperado el 3 de octubre de 2022, de https://ciencia.nasa.gov/ciencia-bordo-de-la-misi%C3%B3n-de-carga-de-spacex-22

Xu, D., Gao, Y., Guo, L., Lin, C., & Sun, Y. (2018). Effect of dys-1 mutation on gene expression profile in space-flown C. elegans. Muscle & Nerve. https://doi.org/10.1002/mus.26076

Honda, Y., Higashibata, A., Matsunaga, Y., Yonezawa, Y., Kawano, T., Higashitani, A., Kuriyama, K., Shimazu, T., Tanaka, M., Szewczyk, N. J., Ishioka, N., & Honda, S. (2012). Genes down-regulated in spaceflight are involved in the control of longevity in Caenorhabditis elegans. Scientific Reports2(1), 487. https://doi.org/10.1038/srep00487

Adenle, A. A., Johnsen, B., & Szewczyk, N. J. (2009). Review of the results from the International C. elegans first experiment (ICE-FIRST). Advances in Space Research: The Official Journal of the Committee on Space Research (COSPAR)44(2), 210–216. https://doi.org/10.1016/j.asr.2009.04.008

Singh, N. K., Blachowicz, A., Checinska, A., Wang, C., & Venkateswaran, K. (2016). Draft genome sequences of two Aspergillus fumigatus strains, isolated from the International Space Station. Genome Announcements4(4). https://doi.org/10.1128/genomeA.00553-16

Knox, B. P., Blachowicz, A., Palmer, J. M., Romsdahl, J., Huttenlocher, A., Wang, C. C. C., Keller, N. P., & Venkateswaran, K. (2016). Characterization of Aspergillus fumigatus isolates from air and surfaces of the International Space Station. MSphere1(5). https://doi.org/10.1128/msphere.00227-16

BBVA openmind (2022,05 de mayo). tardigrados animales con superpoderes. https://www.bbvaopenmind.com/ciencia/biociencias/tardigrados-animales-con-superpoderes/

Laurie J. Abadie,Nathan Cranford,Charles W. Lloyd,Mark J. Shelhamer,Jennifer L. Turner,NASA Human Research Program. (23 february, 2022). The Human Body in Space



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includes science, biology, space flight